Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions.

Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions.

Impaired acrosomal reaction (IAR) of sperm causes male subfertility in humans and animals. Despite compelling evidence about the genetic control over acrosome biogenesis and function, the genomics of IAR is as yet poorly understood, providing no molecular tools for diagnostics. Here we conducted Equ...

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Bibliographic Details
Main Authors: Terje Raudsepp, Molly E McCue, Pranab J Das, Lauren Dobson, Monika Vishnoi, Krista L Fritz, Robert Schaefer, Aaron K Rendahl, James N Derr, Charles C Love, Dickson D Varner, Bhanu P Chowdhary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003139&type=printable

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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003139&type=printable

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