Burkholderia pseudomallei pathogenesis in human skin fibroblasts: A Bsa type III secretion system is involved in the invasion, multinucleated giant cell formation, and cellular damage.

Burkholderia pseudomallei pathogenesis in human skin fibroblasts: A Bsa type III secretion system is involved in the invasion, multinucleated giant cell formation, and cellular damage.

Burkholderia pseudomallei-a causative agent of melioidosis that is endemic in Southeast Asia and Northern Australia-is a Gram-negative bacterium transmitted to humans via inhalation, inoculation through skin abrasions, and ingestion. Melioidosis causes a range of clinical presentations including ski...

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Main Authors: Anek Kaewpan, Taksaon Duangurai, Amporn Rungruengkitkun, Watcharamat Muangkaew, Tapanee Kanjanapruthipong, Niramol Jitprasutwit, Sumate Ampawong, Passanesh Sukphopetch, Narisara Chantratita, Pornpan Pumirat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0261961

Internet

https://doi.org/10.1371/journal.pone.0261961

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