Burkholderia pseudomallei pathogenesis in human skin fibroblasts: A Bsa type III secretion system is involved in the invasion, multinucleated giant cell formation, and cellular damage.

Burkholderia pseudomallei pathogenesis in human skin fibroblasts: A Bsa type III secretion system is involved in the invasion, multinucleated giant cell formation, and cellular damage.

Burkholderia pseudomallei-a causative agent of melioidosis that is endemic in Southeast Asia and Northern Australia-is a Gram-negative bacterium transmitted to humans via inhalation, inoculation through skin abrasions, and ingestion. Melioidosis causes a range of clinical presentations including ski...

Full description

Bibliographic Details
Main Authors:	Anek Kaewpan, Taksaon Duangurai, Amporn Rungruengkitkun, Watcharamat Muangkaew, Tapanee Kanjanapruthipong, Niramol Jitprasutwit, Sumate Ampawong, Passanesh Sukphopetch, Narisara Chantratita, Pornpan Pumirat
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0261961

Similar Items

Cycle-Inhibiting Factor Is Associated with <i>Burkholderia pseudomallei</i> Invasion in Human Neuronal Cells
by: Amporn Rungruengkitkun, et al.
Published: (2022-10-01)

Type VI Secretion System Accessory Protein TagAB-5 Promotes <i>Burkholderia pseudomallei</i> Pathogenicity in Human Microglia
by: Sanisa Lohitthai, et al.
Published: (2023-10-01)

In Vitro Roles of Burkholderia Intracellular Motility A (BimA) in Infection of Human Neuroblastoma Cell Line
by: Niramol Jitprasutwit, et al.
Published: (2023-08-01)

Altered proteome of a Burkholderia pseudomallei mutant defective in short-chain dehydrogenase affects cell adhesion, biofilm formation and heat stress tolerance
by: Onrapak Reamtong, et al.
Published: (2020-03-01)

Development and efficacy of tryptophol-containing emulgel for reducing subcutaneous fungal nodules from Scedosporium apiospermum eumycetoma
by: Thitinan Kitisin, et al.
Published: (2022-01-01)

Infections of Cryptococcus species induce degeneration of dopaminergic neurons and accumulation of α-Synuclein in Caenorhabditis elegans
by: Thitinan Kitisin, et al.
Published: (2022-10-01)

Caenorhabditis elegans DAF-16 regulates lifespan and immune responses to Cryptococcus neoformans and Cryptococcus gattii infections
by: Thitinan Kitisin, et al.
Published: (2022-06-01)

The study of tryptophol containing emulgel on fungal reduction and skin irritation
by: Thitinan Kitisin, et al.
Published: (2023-11-01)

Effect of urea-extracted sericin on melanogenesis: potential applications in post-inflammatory hyperpigmentation
by: Pornanong Aramwit, et al.
Published: (2018-11-01)

Phylogenetic analysis and antibiotic resistance of Escherichia coli isolated from wild and domestic animals at an agricultural land interface area of Salaphra wildlife sanctuary, Thailand
by: Taksaon Duangurai, et al.
Published: (2022-12-01)

High-Dose Primaquine Induces Proximal Tubular Degeneration and Ventricular Cardiomyopathy Linked to Host Cells Mitochondrial Dysregulation
by: Atthasit Rabiablok, et al.
Published: (2023-02-01)

Phenomic profiling of a novel sibling species within the Scedosporium complex in Thailand
by: T. Kitisin, et al.
Published: (2021-02-01)

Tryptophol Coating Reduces Catheter-Related Cerebral and Pulmonary Infections by Scedosporium apiospermum
by: Kitisin T, et al.
Published: (2020-07-01)

Sericin enhances ammonia detoxification by promotes urea cycle enzyme genes and activates hepatic autophagy in relation to CARD-9/MAPK pathway
by: Sumate Ampawong, et al.
Published: (2023-11-01)

Mulberry-Derived 1-Deoxynojirimycin Prevents Type 2 Diabetes Mellitus Progression via Modulation of Retinol-Binding Protein 4 and Haptoglobin
by: Kamonpan Fongsodsri, et al.
Published: (2022-10-01)

Streptozotocin induces alpha-2u globulin nephropathy in male rats during diabetic kidney disease
by: Kanchana Kengkoom, et al.
Published: (2021-03-01)

Characterization of Virulence Factors in <i>Candida</i> Species Causing Candidemia in a Tertiary Care Hospital in Bangkok, Thailand
by: Natnaree Saiprom, et al.
Published: (2023-03-01)

Paracapillaria (Ophidiocapillaria) siamensis sp. nov. (Nematoda: Trichuroidea): A New Nematode in Naja kaouthia from Thailand
by: Vachirapong Charoennitiwat, et al.

Sericin coated thin polymeric films reduce keratinocyte proliferation via the mTOR pathway and epidermal inflammation through IL17 signaling in psoriasis rat model
by: Pornanong Aramwit, et al.
Published: (2023-07-01)

Occurrence, antimicrobial resistance, virulence, and biofilm formation capacity of Vibrio spp. and Aeromonas spp. isolated from raw seafood marketed in Bangkok, Thailand
by: Sirijan Santajit, et al.
Published: (2022-07-01)

Global transcriptional profiling of <it>Burkholderia pseudomallei </it>under salt stress reveals differential effects on the Bsa type III secretion system
by: Singsuksawat Ekapot, et al.
Published: (2010-06-01)

Sericin-Based Poly(Vinyl) Alcohol Relieves Plaque and Epidermal Lesions in Psoriasis; a Chance for Dressing Development in a Specific Area
by: Khwanchanok Tuentam, et al.
Published: (2022-12-01)

Staphylococcus spp. associated with subclinical bovine mastitis in central and northeast provinces of Thailand
by: Natapol Pumipuntu, et al.
Published: (2019-03-01)

Erythroderma and Skin Desquamation in Paederus Dermatitis
by: Thitinan Kitisin, et al.
Published: (2021-01-01)

Analysis of the prevalence, secretion and function of a cell cycle-inhibiting factor in the melioidosis pathogen Burkholderia pseudomallei.
by: Pornpan Pumirat, et al.
Published: (2014-01-01)

Mass spectrometry-based identification and whole-genome characterisation of the first pteropine orthoreovirus isolated from monkey faeces in Thailand
by: Nathamon Kosoltanapiwat, et al.
Published: (2018-10-01)

Human Single-chain Variable Fragments Neutralize Pseudomonas aeruginosa Quorum Sensing Molecule, 3O-C12-HSL, and Prevent Cells From the HSL-mediated Apoptosis
by: Sirijan Santajit, et al.
Published: (2020-06-01)

Regenerative potential of multinucleated cells: bone marrow adiponectin-positive multinucleated cells take the lead
by: Shiva Moein, et al.
Published: (2023-07-01)

Phacoemulsification in a chinchilla (Chinchilla lanigera)
by: Natthanet Sritrakoon, et al.
Published: (2023-08-01)

Case report: Plasmablastic neoplasm with multinucleated giant cells—Analysis of stemness of the neoplastic multinucleated giant cells
by: Narumi Otsuka-Kamakura, et al.
Published: (2022-11-01)

Osteoclast Multinucleation: Review of Current Literature
by: Joe Kodama, et al.
Published: (2020-08-01)

Unilateral Cleavage Furrows in Multinucleate Cells
by: Julia Bindl, et al.
Published: (2020-06-01)

Functional analysis of BPSS2242 reveals its detoxification role in Burkholderia pseudomallei under salt stress
by: Kamonwan Chamchoy, et al.
Published: (2020-06-01)

Identification of Burkholderia pseudomallei Genes Induced During Infection of Macrophages by Differential Fluorescence Induction
by: Siroj Jitprasutwit, et al.
Published: (2020-02-01)

#23 : Correlation of Multinucleated Embryo and Pregnancy Outcome
by: Nuguelis Razali, et al.
Published: (2023-12-01)

Giant Multinucleated Cells in Aging and Senescence—An Abridgement
by: Malgorzata Kloc, et al.
Published: (2022-07-01)

Heterogeneity and Actin Cytoskeleton in Osteoclast and Macrophage Multinucleation
by: Jiro Takito, et al.
Published: (2020-09-01)

Multinucleate cell angiohistiocytoma: a diagnostic challenge
by: Patricia Mayumi Ogawa, et al.
Published: (2023-08-01)

Multinucleation in the Two-Cell Stage Embryo Matters
by: Leah LAZZARO, et al.
Published: (2022-09-01)

Adipoclast: a multinucleated fat-eating macrophage
by: Antoni Olona, et al.
Published: (2021-11-01)