Uridine Inhibits Hepatocellular Carcinoma Cell Development by Inducing Ferroptosis

Uridine Inhibits Hepatocellular Carcinoma Cell Development by Inducing Ferroptosis

Uridine is a key metabolite used as a substrate for the production of DNA, RNA, and glucose, and it is mainly synthesized in the liver. Currently, it is not known whether uridine levels are altered in the tumor microenvironment of patients with hepatocellular carcinoma (HCC) and whether uridine can...

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Bibliographic Details
Main Authors: Liuliu Zi, Wangbin Ma, Lilong Zhang, Boyang Qiao, Zhendong Qiu, Junhui Xu, Jiacheng Zhang, Yahong Ye, Yueyuan Yang, Keshuai Dong, Chen Chen, Weixing Wang, Qingyan Zhao
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Clinical Medicine
Subjects:
hepatocellular carcinoma
tumor microenvironment
CAD
DHODH
uridine
ferroptosis
Online Access:https://www.mdpi.com/2077-0383/12/10/3552

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https://www.mdpi.com/2077-0383/12/10/3552

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