Prophylactic furosemide to prevent transfusion-associated circulatory overload: a randomized controlled study in rats

Abstract Transfusion-associated circulatory overload (TACO) is the leading cause of transfusion related morbidity and mortality. The only treatment is empirical use of furosemide. Our aim was to investigate if furosemide can prevent TACO. A randomized controlled trial was performed using a previousl...

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Bibliographic Details
Main Authors: Robert B. Klanderman, Joachim J. Bosboom, Denise P. Veelo, Joris J. T. H. Roelofs, Dirk de Korte, Robin van Bruggen, Liffert Vogt, Jaap D. van Buul, Markus W. Hollmann, Margreeth B. Vroom, Nicole P. Juffermans, Bart F. Geerts, Alexander P. J. Vlaar
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16465-z