The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment

The Raf Kinase Inhibitor Protein (RKIP) is a unique gene product that directly inhibits the Raf/Mek/Erk and NF-kB pathways in cancer cells and resulting in the inhibition of cell proliferation, viability, EMT, and metastasis. Additionally, RKIP is involved in the regulation of cancer cell resistance...

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Bibliographic Details
Main Authors: Hannah Cessna, Stavroula Baritaki, Apostolos Zaravinos, Benjamin Bonavida
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/19/4596