The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment
The Raf Kinase Inhibitor Protein (RKIP) is a unique gene product that directly inhibits the Raf/Mek/Erk and NF-kB pathways in cancer cells and resulting in the inhibition of cell proliferation, viability, EMT, and metastasis. Additionally, RKIP is involved in the regulation of cancer cell resistance...
Main Authors: | Hannah Cessna, Stavroula Baritaki, Apostolos Zaravinos, Benjamin Bonavida |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-09-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/14/19/4596 |
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