Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels

Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels

ATP-sensitive potassium (KATP) channels link cell metabolism to membrane excitability and are involved in a wide range of physiological processes including hormone secretion, control of vascular tone, and protection of cardiac and neuronal cells against ischemic injuries. In pancreatic β-cells, KATP...

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Bibliographic Details
Main Authors: Gregory M. Martin, Pei-Chun eChen, Prasanna eDevaraneni, Show-Ling eShyng
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Physiology
Subjects:
Carbamazepine
pharmacological chaperone
Sulfonylurea
Congenital Hyperinsulinism (CHI)
ATP-sensitive potassium channel
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00386/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00386/full

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