Spatial and single-cell explorations uncover prognostic significance and immunological functions of mitochondrial calcium uniporter in breast cancer

Spatial and single-cell explorations uncover prognostic significance and immunological functions of mitochondrial calcium uniporter in breast cancer

Abstract The mitochondrial calcium uniporter (MCU) is a transmembrane protein facilitating the entry of calcium ions into mitochondria from the cell cytosol. Maintaining calcium balance is crucial for enhancing cellular energy supply and regulating cell death. The interplay of calcium balance throug...

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Bibliographic Details
Main Authors: Chia-Jung Li, Yen-Dun Tony Tzeng, Jui-Hu Hsiao, Ling-Ming Tseng, Tzu-Sheng Hsu, Pei-Yi Chu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Cancer Cell International
Subjects:
MCU
Immune infiltration
Breast cancer
Single-cell RNA-sequencing
Spatial transcriptomics
Online Access:https://doi.org/10.1186/s12935-024-03327-z

Internet

https://doi.org/10.1186/s12935-024-03327-z

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