Aerobic exercise improves cognitive impairment in mice with type 2 diabetes by regulating the MALAT1/miR-382-3p/BDNF signaling pathway in serum-exosomes

Aerobic exercise improves cognitive impairment in mice with type 2 diabetes by regulating the MALAT1/miR-382-3p/BDNF signaling pathway in serum-exosomes

Abstract Background It has been documented that aerobic exercise (AE) has a positive effect on improving cognitive function in type 2 diabetes (T2DM) patients. Here, we tried to explore how AE regulates the expression of long non-coding RNA in serum-exosomes (Exos), thereby affecting cognitive impai...

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Bibliographic Details
Main Authors: Mingzhu Wang, Kangling Xie, Shengnan Zhao, Nan Jia, Yujiao Zong, Wenping Gu, Ying Cai
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Molecular Medicine
Subjects:
Aerobic exercise
Serum-exosomes
Non-coding RNA
Type 2 diabetes
Hippocampal neurons
MALAT1
Online Access:https://doi.org/10.1186/s10020-023-00727-1

Internet

https://doi.org/10.1186/s10020-023-00727-1

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