Marginal Zone Formation Requires ACKR3 Expression on B Cells

Marginal Zone Formation Requires ACKR3 Expression on B Cells

Summary: The marginal zone (MZ) contributes to the highly organized spleen microarchitecture. We show that expression of atypical chemokine receptor 3 (ACKR3) defines two equal-sized populations of mouse MZ B cells (MZBs). ACKR3 is required for development of a functional MZ and for positioning of M...

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Bibliographic Details
Main Authors: Egle Radice, Rafet Ameti, Serena Melgrati, Mathilde Foglierini, Paola Antonello, Rolf A.K. Stahl, Sylvia Thelen, David Jarrossay, Marcus Thelen
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
ACKR3
CXCR4
CXCR5
chemokine
atypical chemokine receptor
marginal zone B cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720309323

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http://www.sciencedirect.com/science/article/pii/S2211124720309323

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