Treatment Trials for Neonatal Seizures: The Effect of Design on Sample Size.

Neonatal seizures are common in the neonatal intensive care unit. Clinicians treat these seizures with several anti-epileptic drugs (AEDs) to reduce seizures in a neonate. Current AEDs exhibit sub-optimal efficacy and several randomized control trials (RCT) of novel AEDs are planned. The aim of this...

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Bibliographic Details
Main Authors: Nathan J Stevenson, Geraldine B Boylan, Lena Hellström-Westas, Sampsa Vanhatalo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5100925?pdf=render