Synthesis of β-Cyclodextrin-Decorated Dendritic Compounds Based on EDTA Core: A New Class of PAMAM Dendrimer Analogs

Synthesis of β-Cyclodextrin-Decorated Dendritic Compounds Based on EDTA Core: A New Class of PAMAM Dendrimer Analogs

In this work, two dendritic molecules containing an ethylenediaminetetraacetic acid (EDTA) core decorated with two and four β-cyclodextrin (βCD) units were synthesized and fully characterized. Copper(I)-catalyzed alkyne–azide cycloaddition (CuAAC) click chemistry under microwave irradiation was used...

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Bibliographic Details
Main Authors: Israel González-Méndez, Esteban Loera-Loera, Kendra Sorroza-Martínez, Mireille Vonlanthen, Fabián Cuétara-Guadarrama, María Josefa Bernad-Bernad, Ernesto Rivera, Jesús Gracia-Mora
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
EDTA dendrimer
β-cyclodextrin
click chemistry
PAMAM dendrimer
microwave assisted synthesis
Online Access:https://www.mdpi.com/1999-4923/14/11/2363

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https://www.mdpi.com/1999-4923/14/11/2363

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