Structural insights into the molecular mechanism of the m6A writer complex

Structural insights into the molecular mechanism of the m6A writer complex

Methylation of adenosines at the N6 position (m6A) is a dynamic and abundant epitranscriptomic mark that regulates critical aspects of eukaryotic RNA metabolism in numerous biological processes. The RNA methyltransferases METTL3 and METTL14 are components of a multisubunit m6A writer complex whose e...

Full description

Bibliographic Details
Main Authors: Paweł Śledź, Martin Jinek
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
RNA
methyltransferase
m6A
epitranscriptomics
post-transcriptional gene regulation
X-ray crystallography
Online Access:https://elifesciences.org/articles/18434

Internet

https://elifesciences.org/articles/18434

Similar Items