Identifying Drug Targets of Oral Squamous Cell Carcinoma through a Systems Biology Method and Genome-Wide Microarray Data for Drug Discovery by Deep Learning and Drug Design Specifications

Identifying Drug Targets of Oral Squamous Cell Carcinoma through a Systems Biology Method and Genome-Wide Microarray Data for Drug Discovery by Deep Learning and Drug Design Specifications

In this study, we provide a systems biology method to investigate the carcinogenic mechanism of oral squamous cell carcinoma (OSCC) in order to identify some important biomarkers as drug targets. Further, a systematic drug discovery method with a deep neural network (DNN)-based drug–target interacti...

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Bibliographic Details
Main Authors: Yi-Chung Lin, Bor-Sen Chen
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
oral squamous cell carcinoma (OSCC)
deep neural network-based drug–target interaction (DNN-based DTI) model
genome-wide genetic and epigenetic network (GWGEN)
significant biomarkers
drug design specifications
Online Access:https://www.mdpi.com/1422-0067/23/18/10409

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https://www.mdpi.com/1422-0067/23/18/10409

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