Profiling the Concentration of Reduced and Oxidized Glutathione in Rat Brain Using HPLC/DAD Chromatographic System

This study aimed to develop a HPLC/DAD method in order to determine and quantify the reduced glutathione (GSH) and oxidized glutathione (GSSG) levels in rat brain. Due to the presence of the thiol group (-SH), GSH can interact with the Ellman′s reagent (DTNB), with which it forms a reaction product...

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Bibliographic Details
Main Authors: George Jîtcă, Erzsébet Fogarasi, Bianca-Eugenia Ősz, Camil Eugen Vari, Ibolya Fülöp, Mircea Dumitru Croitoru, Carmen Maria Rusz, Maria Titica Dogaru
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/21/6590