T-cell infiltration and its regulatory mechanisms in cancers: insights at single-cell resolution

T-cell infiltration and its regulatory mechanisms in cancers: insights at single-cell resolution

Abstract Tumor-infiltrating T cells recognize, attack, and clear tumor cells, playing a central role in antitumor immune response. However, certain immune cells can impair this response and help tumor immune escape. Therefore, exploring the factors that influence T-cell infiltration is crucial to un...

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Bibliographic Details
Main Authors: Wenhui Yang, Shimao Liu, Mengyun Mao, Yandong Gong, Xiaohui Li, Tianyu Lei, Chao Liu, Shikai Wu, Qinyong Hu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Single-cell RNA sequencing
Tumor microenvironment
T-cell infiltration
“hot tumors” and “cold tumors”
Stromal cells
Online Access:https://doi.org/10.1186/s13046-024-02960-w

Internet

https://doi.org/10.1186/s13046-024-02960-w

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