Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury

Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury

Summary: Recent trends suggest novel natural compounds as promising treatments for cardiovascular disease. The authors examined how neopetroside A, a natural pyridine nucleoside containing an α-glycoside bond, regulates mitochondrial metabolism and heart function and investigated its cardioprotectiv...

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Bibliographic Details
Main Authors: Hyoung Kyu Kim, PhD, Min Kim, PhD, Jubert C. Marquez, PhD, Seung Hun Jeong, PhD, Tae Hee Ko, PhD, Yeon Hee Noh, MS, Pham Trong Kha, PhD, Ha Min Choi, BS, Dong Hyun Kim, PhD, Jong Tae Kim, PhD, Young Il Yang, PhD, Kyung Soo Ko, PhD, Byoung Doo Rhee, PhD, Larisa K. Shubina, PhD, Tatyana N. Makarieva, PhD, Dmitry Y. Yashunsky, PhD, Alexey G. Gerbst, PhD, Nikolay E. Nifantiev, PhD, Valentin A. Stonik, PhD, Jin Han, PhD
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:JACC: Basic to Translational Science
Subjects:
GSK-3β inhibition
ischemia/reperfusion injury
marine pyridine α-nucleoside
mitochondria
NPS A
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X22001942

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http://www.sciencedirect.com/science/article/pii/S2452302X22001942

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