Circular RNA circSDHC serves as a sponge for miR-127-3p to promote the proliferation and metastasis of renal cell carcinoma via the CDKN3/E2F1 axis

Circular RNA circSDHC serves as a sponge for miR-127-3p to promote the proliferation and metastasis of renal cell carcinoma via the CDKN3/E2F1 axis

Abstract Background There is increasing evidence that circular RNAs (circRNAs) have significant regulatory roles in cancer development and progression; however, the expression patterns and biological functions of circRNAs in renal cell carcinoma (RCC) remain largely elusive. Method Bioinformatics me...

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Bibliographic Details
Main Authors: Junjie Cen, Yanping Liang, Yong Huang, Yihui Pan, Guannan Shu, Zhousan Zheng, Xiaozhong Liao, Mi Zhou, Danlei Chen, Yong Fang, Wei Chen, Junhang Luo, Jiaxing Zhang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Molecular Cancer
Subjects:
circSDHC
E2F1 pathway
miR-127-3p
Renal cell carcinoma
Online Access:https://doi.org/10.1186/s12943-021-01314-w

Internet

https://doi.org/10.1186/s12943-021-01314-w

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