The low levels of eicosapentaenoic acid in rat brain phospholipids are maintained via multiple redundant mechanisms

Brain eicosapentaenoic acid (EPA) levels are 250- to 300-fold lower than docosahexaenoic acid (DHA), at least partly, because EPA is rapidly β-oxidized and lost from brain phospholipids. Therefore, we examined if β-oxidation was necessary for maintaining low EPA levels by inhibiting β-oxidation with...

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Bibliographic Details
Main Authors: Chuck T. Chen, Anthony F. Domenichiello, Marc-Olivier Trépanier, Zhen Liu, Mojgan Masoodi, Richard P. Bazinet
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520351312