Eltrombopag Preserves the Clonogenic Potential of Hematopoietic Stem Cells During Treatment With Antithymocyte Globulin in Patients With Aplastic Anemia

Eltrombopag Preserves the Clonogenic Potential of Hematopoietic Stem Cells During Treatment With Antithymocyte Globulin in Patients With Aplastic Anemia

Aplastic anemia (AA) is frequently caused by a T-cell mediated autoimmune depletion of the hematopoietic stem and progenitor cell (HSPC) compartment. Immunosuppressive therapy (IST) with antithymocyte globulin (ATG) and cyclosporine represents the first-line treatment of AA. One side effect of ATG t...

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Bibliographic Details
Main Authors: Margherita Vieri, Benjamin Rolles, Maria Crocioni, Mirle Schemionek-Reinders, Susanne Isfort, Jens Panse, Tim H. Brümmendorf, Fabian Beier
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000906

Internet

http://journals.lww.com/10.1097/HS9.0000000000000906

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