Vitamin D (1α,25(OH)2D3) supplementation minimized multinucleated giant cells formation and inflammatory response during Burkholderia pseudomallei infection in human lung epithelial cells

Vitamin D (1α,25(OH)2D3) supplementation minimized multinucleated giant cells formation and inflammatory response during Burkholderia pseudomallei infection in human lung epithelial cells

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Melioidosis is an infectious disease with high mortality rates in human, caused by the bacterium Burkholderia pseudomallei. As an intracellular pathogen, B. pseudomallei can escape from the phagosome and induce multinucleated giant cells (MNGCs) formation resulting in antibiotic resistance and immun...

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Bibliographic Details
Main Authors: Pohnratchada Mattrasongkram, Saharut Wongkaewkhiaw, Suwimol Taweechaisupapong, Sorujsiri Chareonsudjai, Teerasit Techawiwattanaboon, Thararin Ngamsiri, Sakawrat Kanthawong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910702/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910702/?tool=EBI

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