The synergistic and enhancive effects of IL-6 and M-CSF to expand and differentiate functional dendritic cells from human monocytes under serum-free condition

Abstract Background Dendritic cells (DCs) are differentiated from monocytes, and have a strong ability to perform phagocytosis, present antigens and activate T cell immune response. Therefore, DCs are one of the key factors in fighting cancer in immunotherapy, and it is an important issue to develop...

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Bibliographic Details
Main Authors: Chao-Ling Yao, Tsung-Yu Tseng
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Biological Engineering
Subjects:
Online Access:https://doi.org/10.1186/s13036-023-00325-z