Radiolysis-Associated Decrease in Radiochemical Purity of <sup>177</sup>Lu-Radiopharmaceuticals and Comparison of the Effectiveness of Selected Quenchers against This Process

Radiolysis-Associated Decrease in Radiochemical Purity of <sup>177</sup>Lu-Radiopharmaceuticals and Comparison of the Effectiveness of Selected Quenchers against This Process

The radiolytic degradation of vector molecules is a major factor affecting the shelf life of therapeutic radiopharmaceuticals. The development of time-stable dosage forms of radiopharmaceuticals is the key to their successful implementation in clinical practice. Using [<sup>177</sup>Lu]L...

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Bibliographic Details
Main Authors: Anton Larenkov, Iurii Mitrofanov, Ekaterina Pavlenko, Marat Rakhimov
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
therapeutic radiopharmaceuticals
radiolysis
stability
radical scavengers
antioxidants
radiochemical purity
Online Access:https://www.mdpi.com/1420-3049/28/4/1884

Internet

https://www.mdpi.com/1420-3049/28/4/1884

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