Zoledronate/Anti-VEGF Neutralizing Antibody Combination Administration Increases Osteal Macrophages in a Murine Model of MRONJ Stage 0-like Lesions
The pathophysiology, pathogenesis, histopathology, and immunopathology of medication-related osteonecrosis of the jaw (MRONJ) Stage 0 remain unclear, although 50% of MRONJ Stage 0 cases could progress to higher stages. The aim of this study was to investigate the effects of zoledronate (Zol) and ant...
Main Authors: | Haruka Kaneko, Shinichiro Kuroshima, Ryohei Kozutsumi, Farah A. Al-Omari, Hiroki Hayano, Kazunori Nakajima, Takashi Sawase |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
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Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/12/5/1914 |
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