Antithrombotic and prohemorrhagic actions of different concentrations of apixaban in patients exposed to single and dual antiplatelet regimens

Abstract We evaluated modifications in the hemostatic balance of different concentrations of apixaban (APIX) in 25 healthy donors and 53 patients treated with aspirin (ASA, n = 21), ASA and clopidogrel (ASA + CLOPI, n = 11), or ASA and ticagrelor (ASA + TICA, n = 21). Blood samples from participants...

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Bibliographic Details
Main Authors: Julia Martinez-Sanchez, Leticia Castrillo, Didac Jerez, Sergi Torramade-Moix, Marta Palomo, Guiomar Mendieta, M. Urooj Zafar, Ana Belén Moreno-Castaño, Pablo Sanchez, Juan Jose Badimon, Maribel Diaz-Ricart, Gines Escolar, Mercè Roqué
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50347-2