Vascular Remodeling in Pulmonary Arterial Hypertension: The Potential Involvement of Innate and Adaptive Immunity

Vascular Remodeling in Pulmonary Arterial Hypertension: The Potential Involvement of Innate and Adaptive Immunity

Pulmonary arterial hypertension (PAH) is a severe disease with high morbidity and mortality. Current therapies are mainly focused on vasodilative agents to improve prognosis. However, recent literature has shown the important interaction between immune cells and stromal vascular cells in the pathoge...

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Bibliographic Details
Main Authors: Rachid Tobal, Judith Potjewijd, Vanessa P. M. van Empel, Renee Ysermans, Leon J. Schurgers, Chris P. Reutelingsperger, Jan G. M. C. Damoiseaux, Pieter van Paassen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Medicine
Subjects:
pulmonary arterial hypertension
immunology
vascular remodeling
endotheliopathy
macrophage
histology
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.806899/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.806899/full

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