Human phenotype ontology annotation and cluster analysis for pulmonary atresia to unravel clinical outcomes

Human phenotype ontology annotation and cluster analysis for pulmonary atresia to unravel clinical outcomes

BackgroundPulmonary atresia (PA) is a heterogeneous congenital heart defect and ventricular septal defect (VSD) is the most vital factor for the conventional classification of PA patients. The simple dichotomy could not fully describe the cardiac morphologies and pathophysiology in such a complex di...

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Bibliographic Details
Main Authors: Bingyan Shu, Huayan Shen, Xinyang Shao, Fengming Luo, Tianjiao Li, Zhou Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
pulmonary atresia
Human Phenotype Ontology
unsupervised cluster analysis
Kaplan-Meier curves
Cox proportional hazards regression
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.898289/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.898289/full

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