Biosynthesis of eicosanoids and transcellular metabolism of leukotrienes in murine bone marrow cells
Leukotriene B4 (LTB4) biosynthesis by polymorphonuclear leukocytes (PMNs) is an important factor of inflammatory responses. PMNs also release LTA4, an unstable intermediate that can be taken up by neighboring cells and metabolized into LTC4. Most studies of LT synthesis have been carried out using h...
Main Authors: | Miguel A. Gijón, Simona Zarini, Robert C. Murphy |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-03-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752043247X |
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