Experimental evaluation of super-resolution imaging and magnification choice in single-particle cryo-EM
The resolution of cryo-EM reconstructions is fundamentally limited by the Nyquist frequency, which is half the sampling frequency of the detector and depends upon the magnification used. In principle, super-resolution imaging should enable reconstructions to surpass the physical Nyquist limit by inc...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Journal of Structural Biology: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590152421000040 |