High Throughput Screening for Natural Host Defense Peptide-Inducing Compounds as Novel Alternatives to Antibiotics

High Throughput Screening for Natural Host Defense Peptide-Inducing Compounds as Novel Alternatives to Antibiotics

A rise in antimicrobial resistance demands novel alternatives to antimicrobials for disease control and prevention. As an important component of innate immunity, host defense peptides (HDPs) are capable of killing a broad spectrum of pathogens and modulating a range of host immune responses. Enhanci...

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Bibliographic Details
Main Authors: Wentao Lyu, Zhuo Deng, Lakshmi T. Sunkara, Sage Becker, Kelsy Robinson, Robert Matts, Guolong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
host defense peptides
antimicrobial peptides
defensins
high throughput screening
HDP inducers
wortmannin
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00191/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2018.00191/full

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