The Increase of the Magnitude of Spontaneous Viral Blips in Some Participants of Phase II Clinical Trial of Therapeutic Optimized HIV DNA Vaccine Candidate

The Increase of the Magnitude of Spontaneous Viral Blips in Some Participants of Phase II Clinical Trial of Therapeutic Optimized HIV DNA Vaccine Candidate

We developed a candidate DNA vaccine called “DNA-4”consisting of 4 plasmid DNAs encoding Nef, Gag, Pol(rt), and gp140 HIV-1 proteins. The vaccine was found to be safe and immunogenic in a phase I clinical trial. Here we present the results of a phase II clinical trial of &#82...

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Bibliographic Details
Main Authors: Ekaterina Akulova, Boris Murashev, Sergey Verevochkin, Alexey Masharsky, Ruslan Al-Shekhadat, Valeriy Poddubnyy, Olga Zozulya, Natalia Vostokova, Andrei P. Kozlov
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Vaccines
Subjects:
HIV
AIDS
DNA vaccine
clinical trial
therapeutic vaccine
Online Access:https://www.mdpi.com/2076-393X/7/3/92

Internet

https://www.mdpi.com/2076-393X/7/3/92

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