Deciphering the state of immune silence in fatal COVID-19 patients

Integrated studies of matched tissue sites and cell types in COVID-19 patients are important to define the immune mechanisms of pathology. Here, the authors describe an immune signature in fatal COVID-19 patients harmonizing single-cell RNA sequencing of blood and matched BAL cells with deep clinica...

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Bibliographic Details
Main Authors: Pierre Bost, Francesco De Sanctis, Stefania Canè, Stefano Ugel, Katia Donadello, Monica Castellucci, David Eyal, Alessandra Fiore, Cristina Anselmi, Roza Maria Barouni, Rosalinda Trovato, Simone Caligola, Alessia Lamolinara, Manuela Iezzi, Federica Facciotti, Annarita Mazzariol, Davide Gibellini, Pasquale De Nardo, Evelina Tacconelli, Leonardo Gottin, Enrico Polati, Benno Schwikowski, Ido Amit, Vincenzo Bronte
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21702-6