Mechanically induced pyroptosis enhances cardiosphere oxidative stress resistance and metabolism for myocardial infarction therapy

Abstract Current approaches in myocardial infarction treatment are limited by low cellular oxidative stress resistance, reducing the long-term survival of therapeutic cells. Here we develop a liquid-crystal substrate with unique surface properties and mechanical responsiveness to produce size-contro...

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Bibliographic Details
Main Authors: Yingwei Wang, Qi Li, Jupeng Zhao, Jiamin Chen, Dongxue Wu, Youling Zheng, Jiaxin Wu, Jie Liu, Jianlong Lu, Jianhua Zhang, Zheng Wu
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41700-0