Pathogenesis and novel therapeutics of regulatory T cell subsets and interleukin-2 therapy in systemic lupus erythematosus

Pathogenesis and novel therapeutics of regulatory T cell subsets and interleukin-2 therapy in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a heterogeneous multisystem inflammatory disease with wide variability in clinical manifestations. Natural arising CD4+ regulatory T cells (Tregs) play a critical role in maintaining peripheral tolerance by suppressing inflammation and preventing autoimmune resp...

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Bibliographic Details
Main Authors: Yi-Giien Tsai, Pei-Fen Liao, Kai-Hung Hsiao, Hung-Ming Wu, Ching-Yuang Lin, Kuender D. Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
lupus nephritis
regulatory T cells
interleukin-2
B regulatory cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1230264/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1230264/full

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