The Dying Forward Hypothesis of ALS: Tracing Its History
The site of origin of amyotrophic lateral sclerosis (ALS), although unsettled, is increasingly recognized as being cortico-fugal, which is a dying-forward process primarily starting in the corticomotoneuronal system. A variety of iterations of this concept date back to over 150 years. Recently, the...
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Format: | Article |
Language: | English |
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MDPI AG
2021-02-01
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Series: | Brain Sciences |
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Online Access: | https://www.mdpi.com/2076-3425/11/3/300 |