Identification of natural inhibitor from Aframomum melegueta targeting survivin and mammalian rapamycin signaling pathway in Kidney Cancer

Identification of natural inhibitor from Aframomum melegueta targeting survivin and mammalian rapamycin signaling pathway in Kidney Cancer

Overactivation of survivin and mammalian rapamycin signaling pathway plays an important role in renal carcinogenesis. Recent studies have shown that extract from Aframomum species produces interesting cytotoxic effects against drug resistance cancer. However, the effect of Aframomum melegueta on ren...

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Bibliographic Details
Main Authors: Olusola Olalekan Elekofehinti, Precious Ayomide Ajiboro, Moses Orimoloye Akinjiyan, Tolulope Peter Saliu, Folasade Oluwatobiloba Ayodeji, Funmilola Mabel Ojo, Cecilia Oluwamodupe
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Aframomum melegueta
Molecular docking
Kidney cancer
Survivin
Mammalian rapamycin signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914823001661

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http://www.sciencedirect.com/science/article/pii/S2352914823001661

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