Differential Inhibitory Effects of Curcumin Between HPV+ve and HPV–ve Oral Cancer Stem Cells

Differential Inhibitory Effects of Curcumin Between HPV+ve and HPV–ve Oral Cancer Stem Cells

Aim: To investigate the role of a herbal antioxidative compound curcumin on cell proliferation, orosphere formation and miRNA-21 expression in HPV16+ve/–ve oral cancer stem cells.Materials and Methods: Oral cancer stem cells were isolated from HPV+ve/HPV–ve oral cancer cell lines by FACS and stemnes...

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Bibliographic Details
Main Authors: Nasreen Bano, Manisha Yadav, Bhudev C. Das
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Oncology
Subjects:
cancer stem cells (CSCs)
oral squamous cell carcinoma (OSCC)
curcumin
human papillomavirus (HPV)
SP cells (side population)
stemness
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00412/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00412/full

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