Infection of Dendritic Cells With Mycobacterium avium subspecies hominissuis Exhibits a Functionally Tolerogenic Phenotype in Response to Toll-Like Receptor Agonists via IL-10/Cox2/PGE2/EP2 Axis

Infection of Dendritic Cells With Mycobacterium avium subspecies hominissuis Exhibits a Functionally Tolerogenic Phenotype in Response to Toll-Like Receptor Agonists via IL-10/Cox2/PGE2/EP2 Axis

Mycobacterium avium subspecies hominissuis (MAH) is the most common agent causing nontuberculous mycobacterial disease in humans. It mainly causes chronic and slowly progressive pulmonary disease (PD), which requires a long-term treatment and allows opportunistic co-infection by common pulmonary pat...

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Bibliographic Details
Main Authors: Woo Sik Kim, Joo-Heon Yoon, Min-Kyoung Shin, Sung Jae Shin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium avium subspecies hominissuis
dendritic cells
interleukin-10
toll-like receptor4
Cox-2/PGE2 signaling
EP2 receptor
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01795/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01795/full

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