Placental stem cells-derived exosomes stimulate cutaneous wound regeneration via engrailed-1 inhibition

Introduction: Skin wounds generally heal by scarring, a fibrotic process mediated by the Engrailed-1 (EN1) fibroblast lineage. Scar is detrimental to tissue structure and function, but perfect healing in clinical settings remains to be explored. Recent studies have shown that mesenchymal stem cell (...

Full description

Bibliographic Details
Main Authors: Yan Zhang, Liyan Shi, Xiuying Li, Yang Liu, Guokun Zhang, Yimin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1044773/full