Inhibition of Multifunctional Protein p32/C1QBP Promotes Cytostatic Effects in Colon Cancer Cells by Altering Mitogenic Signaling Pathways and Promoting Mitochondrial Damage

Inhibition of Multifunctional Protein p32/C1QBP Promotes Cytostatic Effects in Colon Cancer Cells by Altering Mitogenic Signaling Pathways and Promoting Mitochondrial Damage

The protein p32 (C1QBP) is a multifunctional and multicompartmental homotrimer that is overexpressed in many cancer types, including colon cancer. High expression levels of C1QBP are negatively correlated with the survival of patients. Previously, we demonstrated that C1QBP is an essential promoter...

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Bibliographic Details
Main Authors: Carlos Alejandro Egusquiza-Alvarez, Angela Patricia Moreno-Londoño, Eduardo Alvarado-Ortiz, María del Pilar Ramos-Godínez, Miguel Angel Sarabia-Sánchez, María Cristina Castañeda-Patlán, Martha Robles-Flores
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
p32/gC1qR/C1QBP/HABP1
colon cancer
M36 inhibitor
cytostatic effects
mitochondrial dynamics
mitochondrial damage
Online Access:https://www.mdpi.com/1422-0067/25/5/2712

Internet

https://www.mdpi.com/1422-0067/25/5/2712

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