Ligand-induced activation and G protein coupling of prostaglandin F2α receptor
Abstract Prostaglandin F2α (PGF2α), an endogenous arachidonic acid metabolite, regulates diverse physiological functions in many tissues and cell types through binding and activation of a G-protein-coupled receptor (GPCR), the PGF2α receptor (FP), which also is the primary therapeutic target for gla...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-38411-x |