Tianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation of Arginase-Ornithine Pathway

Tianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation of Arginase-Ornithine Pathway

Background: Pulmonary Fibrosis (PF) is an interstitial lung disease characterized by excessive accumulation of extracellular matrix in the lungs, which disrupts the structure and gas exchange of the alveoli. There are only two approved therapies for PF, nintedanib (Nib) and pirfenidone. Therefore, t...

Full description

Bibliographic Details
Main Authors: Lili Zhang, Sihao Qu, Lu Wang, Chunguo Wang, Qinghe Yu, Zhimin Zhang, Yirui Diao, Binbin Zhang, Yadong Li, Yuanyuan Shi, Peng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
proteomics
tianlong kechuanling
pulmonary fibrosis
arginase
arginase-ornithine pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.661129/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.661129/full

Similar Items