Identification of novel alternative splicing biomarkers for breast cancer with LC/MS/MS and RNA-Seq

Abstract Background Alternative splicing isoforms have been reported as a new and robust class of diagnostic biomarkers. Over 95% of human genes are estimated to be alternatively spliced as a powerful means of producing functionally diverse proteins from a single gene. The emergence of next-generati...

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Bibliographic Details
Main Authors: Fan Zhang, Chris K. Deng, Mu Wang, Bin Deng, Robert Barber, Gang Huang
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-020-03824-8