Adenylate cyclase A amplification and functional diversification during Polyspondylium pallidum development

Abstract Background In Dictyostelium discoideum (Ddis), adenylate cyclase A (ACA) critically generates the cAMP oscillations that coordinate aggregation and morphogenesis. Unlike group 4 species like Ddis, other groups do not use extracellular cAMP to aggregate. However, deletion of cAMP receptors (...

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Bibliographic Details
Main Authors: Yoshinori Kawabe, Pauline Schaap
Format: Article
Language:English
Published: BMC 2022-10-01
Series:EvoDevo
Subjects:
Online Access:https://doi.org/10.1186/s13227-022-00203-7