Molecular characterization of MAP9 in the photoreceptor sensory cilia as a modifier in canine RPGRIP1-associated cone-rod dystrophy

Molecular characterization of MAP9 in the photoreceptor sensory cilia as a modifier in canine RPGRIP1-associated cone-rod dystrophy

Photoreceptors possess a highly specialized primary cilium containing expanded ciliary membrane discs called the outer segment. The photoreceptor cilium is essential for the maintenance of the outer segment, and pathogenic variants in more than 50 cilia-related genes have been identified as causing...

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Bibliographic Details
Main Authors: Kei Takahashi, Jennifer C. Kwok, Yu Sato, Gustavo D. Aguirre, Keiko Miyadera
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
animal model
canine
inherited retinal diseases
MAP9
microtubule-binding protein
photoreceptor
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1226603/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1226603/full

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