A systematic overexpression approach reveals native targets to increase squalene production in Synechocystis sp. PCC 6803

A systematic overexpression approach reveals native targets to increase squalene production in Synechocystis sp. PCC 6803

Cyanobacteria are a promising platform for the production of the triterpene squalene (C30), a precursor for all plant and animal sterols, and a highly attractive intermediate towards triterpenoids, a large group of secondary plant metabolites. Synechocystis sp. PCC 6803 natively produces squalene fr...

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Bibliographic Details
Main Authors: Anna T. Germann, Andreas Nakielski, Maximilian Dietsch, Tim Petzel, Daniel Moser, Sebastian Triesch, Philipp Westhoff, Ilka M. Axmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Plant Science
Subjects:
Synechocystis
squalene
MEP pathway
FBA
metabolic engineering
metabolic modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2023.1024981/full

Internet

https://www.frontiersin.org/articles/10.3389/fpls.2023.1024981/full

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