Real-Time Translocation and Function of PKCβII Isoform in Response to Nociceptive Signaling via the TRPV1 Pain Receptor

Real-Time Translocation and Function of PKCβII Isoform in Response to Nociceptive Signaling via the TRPV1 Pain Receptor

Serine/threonine protein kinase C βII isoform (PKCβII) or the pain receptor transient receptor potential vanilloid 1 (TRPV1) have been separately implicated in mediating heat hyperalgesia during inflammation or diabetic neuropathy. However, detailed information on the role of PKC βII in nociceptive...

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Bibliographic Details
Main Authors: Basil D. Roufogalis, Patricia J. Armati, Sravan Mandadi
Format: Article
Language:English
Published: MDPI AG 2011-11-01
Series:Pharmaceuticals
Subjects:
pain
protein kinase C
transient receptor potential vanilloid-1
real-time translocation
dorsal root ganglion neurons
nociceptive signaling
Online Access:http://www.mdpi.com/1424-8247/4/11/1503/

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http://www.mdpi.com/1424-8247/4/11/1503/

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