Delay-induced uncertainty in the glucose-insulin system: Pathogenicity for obesity and type-2 diabetes mellitus

Delay-induced uncertainty in the glucose-insulin system: Pathogenicity for obesity and type-2 diabetes mellitus

We have recently shown that physiological delay can induce a novel form of sustained temporal chaos we call delay-induced uncertainty (DIU) (Karamched et al. (Chaos, 2021, 31, 023142)). This paper assesses the impact of DIU on the ability of the glucose-insulin system to maintain homeostasis when re...

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Bibliographic Details
Main Authors: Bhargav R. Karamched, George Hripcsak, Rudolph L. Leibel, David Albers, William Ott
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Physiology
Subjects:
delay-induced uncertainty
glucostatic hypothesis
lyapunov exponent
obesity
shear
theory of rank-one maps
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.936101/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.936101/full

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