Inhibition of EMMPRIN and MMP-9 Expression by Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor in PMA-Induced Macrophages

Inhibition of EMMPRIN and MMP-9 Expression by Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor in PMA-Induced Macrophages

Background/Aims: It is well documented that overexpression of EMMPRIN (extracellular matrix metalloproteinase inducer) and MMPs (matrix metalloproteinases) by monocytes/macrophages plays an important role in atherosclerotic plaque rupture. Green tea polyphenol epigallocatechin-3-gallate (EGCG) has a...

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Bibliographic Details
Main Authors: Qi-Ming Wang, Hao Wang, Ya-Fei Li, Zhi-Yong Xie, Yao Ma, Jian-Jun Yan, Yi Fan Wei Gao, Ze-Mu Wang, Lian-Sheng Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Epigallocatechin-3-gallate
67-kDa laminin receptor
MMP-9
EMMPRIN
Stabilization of atherosclerotic plaque
Online Access:http://www.karger.com/Article/FullText/447923

Internet

http://www.karger.com/Article/FullText/447923

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